Le MH, et al. - This study sought to evaluate nonalcoholic fatty liver disease (NAFLD) prevalence and awareness to provide stakeholders necessary information to combat NAFLD burden. A total of 4538 adult individuals were included using data from the National Health and Nutrition Examination Survey 2011–2016 who did not have heavy drinking or viral hepatitis history. The US fatty liver index determined NAFLD and NAFLD fibrosis score marked fibrosis. NAFLD awareness was obtained by the questionnaire. The data showed that NAFLD prevalence was 32.5%, lowest in non-Hispanic blacks (18.0%) and Asians (18.1%), highest amongst Mexican Americans (48.4%) amongst the study population of 4538 persons. It was reported that, of 77.33 million people in the United States have NAFLD with 17.63 million having advanced fibrosis, with the lowest prevalence in non-Hispanic Asians and highest in Mexican Americans. The outcomes indicated that a conundrum exists amongst non-Hispanic Blacks who have low NAFLD prevalence but highest prevalence of advanced fibrosis. The effort is required to increase disease awareness whilst addressing NAFLD clinical burden across ethnicities.