van Leenders GJLH, Kweldam CF, Hollemans E, et al. - Researchers intended to conduct a proof-of-principle study incorporating CR/IDC in the current GG. Between 1993 and 2000, All prostate biopsies of 1,031 men with screen-detected Pca were analyzed for the current GG (ranging from 1 to 5) and CR/IDC. This study recruited a sum of 406 individuals who had received radical prostatectomy (RP), 508 radiotherapies (RT), 108 surveillance, and eight hormonal therapy, and the treatment was unknown for one patient. Utilizing Harrell’s C-statistic, they compared outcome measurements and statistical analysis disease-specific survival (DSS), metastasis-free survival (MFS), and biochemical recurrence-free survival (BCRFS) after 15.1 yr (interquartile range 10.9–19.7 yr) follow-up. Compared with GG, the cGrade is a simple Pca grade modification with better discriminative values for DSS and MFS, especially affecting decision making in men with current GG2 Pca.