Liu J, Zhang Y, Lavie CJ, et al. - Researchers determined if and how C-reactive protein (CRP) and fibrinogen may be related to mortality overall and by gender, race/ethnicity and diet quality among US adults, by analyzing data from the National Health and Nutrition Examination Survey (NHANES) Linked Morality cohort (1999–2011). This study involved 8,646 men and 9,880 women. A median follow-up of 6 years was performed which revealed a strong dose-response link between CRP levels and mortality risk in males following multivariable adjustment. For cardiovascular disease (CVD) mortality, its link with CRP differed by diet quality. For cancer mortality, its link varied by history of cancer, and positive links were noted only in individuals with history of cancer. In this study, lower survival from total and CVD was reported in correlation with higher levels of CRP and fibrinogen; men vs women demonstrated more pronounced links of CRP with mortality. Diet quality was identified as an effect modifier for the link of CRP and fibrinogen with CVD mortality.