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A cross-sectional analysis of the urine microbiome of children with neuropathic bladders

Journal of Pediatric Urology Feb 24, 2020

Forster CS, Panchapakesan K, Stroud C, et al. - The study was sought to define the baseline microbiome in children with neuropathic bladders, and to determine if differences exist among the urine microbiomes of children with neuropathic bladders who have negative urine cultures, asymptomatic bacteriuria (ASB), or urinary tract infection (UTI). Researchers performed a cross-sectional study including a total of 36 children with neuropathic bladders who use clean intermittent catheterization for bladder management who had a urine culture sent as part of clinical management. Via catheter, residual urine initially collected for urine culture, was obtained for use in this work. No difference was found in the urine microbiome between patients with negative urine cultures, ASB, and UTI. Future study is required to whether the urine microbiome varies based on the route of catheterization, or the presence of augmented bladder.
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