Korhonen MJ, et al. – Researchers investigated whether lifestyle factors change in relation to the initiation of antihypertensive or lipid-lowering medication (statins). From the FPS (Finnish Public Sector) study, they assessed 41,225 participants (aged ≥ 40 years) who were free of cardiovascular disease at baseline and responded to ≥ 2 consecutive surveys administered in 4-year intervals in 2000–2013. They assessed pharmacy-claims data for ascertaining medication use. Changes in BMI, physical activity, alcohol consumption, and smoking between 8,837 initiators vs 46,021 non-initiators of antihypertensive medications or statins were assessed using a series of pre–post data sets. Relative to non-initiators, participants initiating medication use exhibited a greater increase in BMI and a greater decline in physical activity, but they displayed a greater decline in average alcohol consumption and higher odds of smoking cessation. According to findings, initiation of antihypertensive and statin medication may be correlated with lifestyle changes—some favorable and others unfavorable. The researchers recommended clinicians to encourage weight management and physical activity in individuals prescribed these medications.