Harmon MBA, Hodiamont CJ, Dankiewicz J, et al. - Researchers conducted a substudy of the TTM trial in order to delineate the microbiological profile of infectious complications in patients with cardiac arrest and to investigate the impact of TTM at 33 °C compared with TTM at 36 °C. In addition, they ascertained the relationship between antibiotic prophylaxis and the incidence of infections. They analyzed 696 patients; of these, 158 (23%) developed pneumonia and 28 (4%) had bacteremia with a clinically relevant pathogen. The most common pathogen isolated was Staphylococcus aureus in patients with pneumonia (23%) and in patients with bacteremia (24%). Overall, gram-negative pathogens were the most common. No influence of TTM on the microbiological profile was evident. They observed reduced risk of infection in significant correlation with the use of antibiotic prophylaxis, however, after correction for clustering within centers, the model did not support the correlation. The outcomes seemed not influenced by adjustment for mortality.