• Profile

Studying the urine microbiome in superficial bladder cancer: Samples obtained by midstream voiding vs cystoscopy

BMC Urology Feb 01, 2020

Hourigan SK, Zhu W, W.Wong WS, et al. - Researchers sought to correlate microbiome metrics resulting from 16S ribosomal RNA gene sequencing between midstream, voided specimens and those obtained at cystoscopy. A total of 22 individuals (8 female, 14 male) were recruited in this study. No significant difference was found in beta diversity (diversity between samples) in all samples between collection methods. Nevertheless, an examination by gender revealed a difference between voided and cystoscopy samples from the same individual in males (p = 0.006, Adonis test) but not in females (p = 0.317, Adonis test). There were no differences by collection method in any alpha diversity (diversity within a sample) measurement or differential abundance of taxa. The data showed that the beta diversity of the urine microbiome did differ by the collection process for males only. It was found that the urinary microbiomes of the two collection methods are not similar to each other, at least in males, which is the gender that bladder cancer occurs most frequently in.
Full text available Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free.
  • 55 lakhs+ doctors trust M3 globally

  • Nonloggedininfinity icon
    Unlimited access to original articles by experts
  • Nonloggedinlock icon
    Secure: we never sell your data
  • Signing up takes less than 2 mins
Try M3 India / Log In
M3 app logo
Choose easy access to M3 India from your mobile!

M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen