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Etiology and outcome of candidemia in neonates and children in Europe: An 11-year multinational retrospective study

The Pediatric Infectious Disease Journal Jan 16, 2020

Warris A, Pana ZD, Oletto A, et al. - Via performing a retrospective multicenter European study, researchers investigated the epidemiology and outcome of neonatal and pediatric candidemia. From 23 hospitals in 10 European countries, they assessed reports on 1,395 episodes of candidemia (57.8% male). Of these, 36.4% were reported in neonates (≤ 44 weeks postmenstrual age), 13.8% in infants (> 44 weeks postmenstrual age to 1 year) and 49.8% in children and adolescents. The species predominantly identified were Candida albicans (52.5%) and Candida parapsilosis (28%). The all-cause mortality of 14.4% was reported at 30 days. Patients admitted to the neonatal or pediatric intensive care units exhibited higher all-cause mortality than other wards. They noted no significant changes in species distribution over time.
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