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Effects of ropivacaine concentration on analgesia after ultrasound-guided serratus anterior plane block: A randomized double-blind trial

Journal of Pain Research Jan 16, 2020

Huang L, Zheng L, Wu B, et al. - Comparison of the analgesic effects of serratus anterior plane (SAP) block with different concentrations of ropivacaine was done. Researchers conducted a randomized double-blind trial inducing SAP block with 20 mL of 0.375%, 0.5%, or 0.75% ropivacaine in 60 patients scheduled for breast surgery. They identified no significant difference in postoperative analgesia in comparison of 0.5% and 0.75% ropivacaine, however, both of these were noted as superior to 0.375% ropivacaine, although higher ropivacaine concentration increased the duration of SAP block. Therefore, in breast surgery, they recommend SAP block with 0.5% ropivacaine for postoperative analgesia.
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