Fasting serum levels of potassium and sodium in relation to long-term risk of cancer in healthy men
Clinical Epidemiology Jan 16, 2020
Falk RS, Heir T, Robsahm TE et al. - Researchers conducted a cohort study to investigate whether serum levels of potassium and sodium were correlated with long-term cancer risk in initially healthy men. For this study, they enrolled 1,994 initially healthy men with no use of medication, aged 40–59 years, was followed for cancer during 40 years of follow-up. They further analyzed correlations between fasting electrolyte levels and cancer risk with incidence rates and Cox proportional hazards models. In healthy men, a positive correlation was found between fasting serum potassium level and long-term cancer risk. They noted that, in cell proliferation or differentiation, potassium or potassium ion channels can play an important role. For targeting individuals with high serum potassium levels, these data might imply future cancer strategies.
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