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Evaluating the 1-h postload glucose level to predict future type 2 diabetes

Diabetes Research and Clinical Practice Jan 16, 2020

Saunajoki AE, et al. - In anticipating the risk of T2D, researchers assessed the predictive ability of 2-h postload glucose level in addition to fasting and 1-h glucose levels. Participants in the study were 654 individuals without T2D at baseline. All individuals had an oral glucose tolerance test, with measurement of glucose at 0, 60, and 120 min at baseline, and after 12 years in a follow-up survey. According to this prospective population-based cohort study, adding 2-h glucose to the fasting model and 1-h glucose levels didn't improve the predictability of new-onset T2D. Compared with fasting (AUC 0.71) and 2-h glucose levels (AUC 0.72), the area under the ROC curve was the largest for 1-h glucose level (AUC 0.81).
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