Baut GL, Kirchgesner J, Amiot A, et al. - Researchers conducted a retrospective analysis of consecutive people with acute severe ulcerative colitis (ASUC) treated with corticosteroids, ciclosporin, or tumor necrosis factor (TNF) antagonists and admitted to 2 hospitals in France from 2002 through 2017, in order to develop a system to discover people risk of colectomy within 1 y of hospital admission for ASUC based on clinical, biomarker, and endoscopy data. In the final analysis, they involved 270 people with ASUC. The cumulative risk of colectomy was 12.3% observed in the derivation cohort. It was found that developing a scoring system to recognize individuals at low-risk than high-risk for colectomy within 1 y of hospitalization for ASUC, on the basis of prior treatment with TNF antagonists or thiopurines, C difficile infection, and serum levels of CRP and albumin. Moreover, in an external cohort, the system was validated.