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Predicting ischemic risk using blood oxygen level-dependent MRI in children with moyamoya

American Journal of Neuroradiology Jan 16, 2020

Dlamini N, Slim M, Kirkham F, et al. - Experts intended to evaluate whether negative blood oxygen level-dependent cerebrovascular reactivity status is predictive of ischemic events in childhood moyamoya. They performed a retrospective study of a consecutive cohort of 37 children with moyamoya (21 female; median age, 10.7 years; interquartile range, 7.5–14.7 years) who underwent evaluation of blood oxygen level-dependent cerebrovascular reactivity for a median of 28.8 months (interquartile range, 13.7–84.1 months). The findings suggest that idiopathic moyamoya and the presence of steal are independently correlated with ischemic events. They found that, for revascularization surgery and the direction of therapy in children with moyamoya, the use of blood oxygen level-dependent cerebrovascular reactivity could potentially assist in the selection of individuals.
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