Sodemann EB, Dähling S, Klopfleisch R, et al. - Researchers performed this study on a mouse model, to determine the impact of maternal allergic airway inflammation during pregnancy on offspring experimental asthma severity and maternal and offspring serum immunoglobulin G (IgG) antibody glycosylation patterns. In addition, they determined the influences of maternal and offspring exposure to the same or different allergens. The included female mice were either sham sensitized or sensitized to casein or ovalbumin prior to mating. Findings revealed a strong connection between maternal experimental asthma during pregnancy, raised offspring airway inflammation and proinflammatory IgG glycosylation patterns in mothers and offspring. In the clinical environment, IgG glycosylation is denied as a standard measurement, and experts argue that it may present as a crucial parameter to incorporate in future clinical investigations.