The association between fasting blood glucose trajectory and cancer risk in Chinese population without diabetes

International Journal of Cancer Jan 12, 2020

Feng X, Wang G, Lyu Z, et al. – Via performing a study involving 69,742 participants without diabetes who were selected from the Kailuan cohort, researchers assessed the links between fasting blood glucose (FBG) trajectories, the alterations in FBG over time, and the risk of cancer, especially for gastrointestinal cancer. Using group-based trajectory modeling, they modeled FBG trajectories (2006-2010) and defined five trajectories: low-increasing (n = 6,275), moderate-stable (n = 44,120), moderate-increasing (n = 10,149), elevated-decreasing (n = 5,244), and elevated-stable (n = 3,954). Compared with the moderate-stable group, the estimated HR for overall cancer was higher in the low-increasing group and was higher for gastrointestinal cancer in the elevated-stable group. For both overall cancer and gastrointestinal cancer, a positive link with the low-increasing group was evident among individuals with an initial BMI ≥ 25 kg/m2, and a positive link with the elevated-stable group was identified among participants with a stable BMI. Among participants without diabetes, there was a link between FBG trajectories and cancer risk. Furthermore, the researchers suggested that BMI may alter these associations.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free.
  • 55 lakhs+ doctors trust M3 globally

  • Nonloggedininfinity icon
    Unlimited access to original articles by experts
  • Nonloggedinlock icon
    Secure: we never sell your data
  • Signing up takes less than 2 mins
Try M3 India / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay