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Midlife socioeconomic position and old-age dementia mortality: A large prospective register-based study from Finland

BMJ Open Jan 12, 2020

Korhonen K, et al. - Researchers conducted a prospective population-based register study in order to evaluate the correlation between multiple indicators of socioeconomic position and dementia-related death and to determine the contribution of dementia to socioeconomic differences in overall mortality at older ages. From the population, aged 70–87 years resident in Finland at the end of the year 2000, 11% random sample was undertaken (n = 54,964). During the 528,387 person-years at risk, 11,395 people died from dementia. Lower midlife education, occupational social class, and household income were correlated with greater dementia mortality, and the differences persisted to the oldest-old ages. The socioeconomic differences emerged later in comparison with mortality from all other causes. Overall indicators of socioeconomic position were autonomously correlated with dementia mortality, low household income was the robustly independent predictor (HR = 1.24) after basic education (HR = 1.14). In comparison with non-manual social class, manual occupational social class was correlated to a 6% higher hazard (HR = 1.06). Outcomes suggest that at older ages, dementia was among the most significant contributors to socioeconomic inequalities in overall mortality.
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