Zhao Y, Jeyaraman K, Burgess P, et al. - Investigators designed the retrospective cohort study utilizing primary care and hospital data routinely used for healthcare in order to assess the profit and risk of low-dose acetylsalicylic acid (aspirin) in individuals from remote aboriginal communities in the Northern Territory, Australia. They involved 8,167 predominantly aboriginal adults and followed in July 2009 and June 2017. Following the matching, aspirin was notably correlated with reduced all-cause mortality (HR = 0.45), however not bleeding (HR = 1.13). Overall Aspirin was correlated with decreased all-cause mortality. In contrast with survival benefits bleeding risk was less. Moreover, Aspirin shall be considered for primary prevention in Aboriginal individuals with great cardiovascular risk.