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Potentially inappropriate prescribing in dementia: A state-of-the-art review since 2007

BMJ Open Jan 10, 2020

Delgado J, et al. - Researchers utilized a state-of-the-art review procedure, selecting papers written in English and published from 2007 to January 2018 in order to determine the prevalence and recognize factors reported to be correlated with, potentially inappropriate prescribing (PIP) for older people diagnosed with dementia. Inclusion measures incorporated a formal diagnosis of dementia, a formal classification of PIP and reported prevalence of PIP as a result. The bibliographic search produced 221 citations, with 12 studies fitting the inclusion standards. The estimates of PIP prevalence for individuals living with dementia ranged from 14% to 64%. Prevalence in the community and nursing/care homes was 31%, 42%, respectively. It was found that PIP persists an important issue in healthcare management for individuals living with dementia. Greater levels of comorbidity were correlated with increased prevalence of PIP, however, the particular conditions driving this progression remain not known. Moreover, work was needed to examine PIP related to the appearance of common comorbidities in people living with dementia.
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