Ehrenwald M, Wasserman A, Shenhar-Tsarfaty S, et al. - Given that resting heart rate (RHR) has been verified as a risk factor for cardiovascular morbidity, it has shown a link with other cardiovascular risk factors, and perhaps foretell them, and alteration in RHR over time (∆RHR) can potentially predict mortality, researchers performed this prospective analysis including 6,683 people without known cardiovascular disease from the TAMCIS: Tel-Aviv Medical Center Inflammation Survey. Among participants, RHR and ∆RHR were assessed at baseline and during 2.9 years as a component of routine check-ups. They assessed ∆RHR via multiple linear regression analysis with three models. They found a reduction in RHR with age, even following adjustment for gender, BMI and metabolic equivalents of task (MET). In both genders, the mean alteration in RHR was estimated to be − 1.1 beats/min between two consecutive visits. There was a strong correlation of this ∆RHR with baseline RHR, age, initial MET, and change occurring in MET and BMI. The necessity of analyzing individual patients’ ∆RHR was highlighted. A positive ∆RHR was identified as an indicator of poor adherence to a healthy lifestyle.