Dai H, Li F, Bragazzi NL, et al. - Among general Chinese adults, researchers ascertained if distinct developmental trajectories of BMI would be predictive of diabetes risk. For this longitudinal study, they recruited 4,519 candidates aged > 18 years who were free of diabetes in 2011. Every year during 2011–2016, all candidates completed a medical examination and BMI levels were measured two to six (average 5.6) times. According to BMI range and changing pattern over time, four distinct BMI trajectories were identified during 2011–2016: “low” (19.6%), “moderate” (33.4%), “moderate-high” (33.4%) and “high” (13.6%). In total, 168 new-onset diabetes cases were confirmed in 2016. Participants in the “high” BMI trajectory were at significantly higher risk for new-onset diabetes compared with the “low” BMI trajectory. The authors discovered that distinct BMI trajectories, even identified using just four or three annual BMI tests, were significantly linked to new-onset diabetes. The results indicate that monitoring of BMI trajectories over time could provide a significant approach in general Chinese adults to identify subpopulations at higher risk of diabetes.