Midlife cardiovascular status and old age physical functioning trajectories in older businessmen

Journal of the American Geriatrics Society Dec 12, 2019

von Bonsdorff MB, et al. - Researchers performed this prospective cohort study to examine the link between cardiovascular status in midlife and physical functioning trajectories in old age. In the Helsinki Businessmen Study, they examined white men born between 1919 and 1934 (HBS, initial n = 3,490). Depending on clinical measurements performed in 1974, three cardiovascular disease (CVD) status groups were defined: signs of CVD (diagnosed clinically or with alterations in ECG, chronic disease present or used medication, n = 563); healthy and low CVD risk (n = 593) and high CVD risk (n = 1222). The optimal number of trajectories was offered by a five-class solution: “intact,” “high stable,” “high and declining,” “intermediate and declining,” and “consistently low” functioning. Findings revealed better development of physical functioning in old age in relation to a more favorable CVD profile in midlife among businessmen.
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