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Associations between skeletal muscle and myocardium in aging: A syndrome of “cardio-sarcopenia”

Journal of the American Geriatrics Society Dec 12, 2019

Keng BMH, Gao F, Teo LLY, et al. - In this study including 378 participants, with 88 (23.3%) individuals having sarcopenia, researchers investigated whether changes in myocardial structure and/or function may exist among aging adults with sarcopenia, leading to a syndrome of “cardio-sarcopenia.” They examined participants from a community cohort study. These people got their skeletal muscle measured in sites such as the trunk, upper limb, and lower limb via same-day bioimpedance body composition analysis and their myocardial structure and function were evaluated via echocardiography. They used the Asian Working Group for Sarcopenia criteria to diagnose sarcopenia. Findings revealed a link between sarcopenia and decreases in left ventricular and left atrial sizes in a community sample of older adults with preserved heart function. An independent link of skeletal muscle mass with specific indices of myocardial structure was also revealed.
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