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Biomarkers that differentiate false positive urinalyses from true urinary tract infection

Pediatric Nephrology Dec 05, 2019

Shaikh N, Martin JM, Hoberman A, et al. – Via performing a prospective cross-sectional study contrasting inflammatory proteins in blood and urine samples obtained at the time of a presumptive diagnosis of UTI, experts identified more precise screening tests that could decrease the number of children who needlessly receive antimicrobials to treat a suspected UTI. A total of 200 children were enrolled; of these, 89 were later shown not to have a UTI based on results of the urine culture received. Urinary proteins involved in the inflammatory response may be beneficial in distinguishing pediatric patients with false positive results with current screening tests for UTI, and this may reduce unnecessary treatment.

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