Ten-year mortality, disease progression, and treatment-related side effects in men with localized prostate cancer from the ProtecT randomized controlled trial according to treatment received

European Urology Dec 04, 2019

Neal DE, Metcalfe C, Donovan JL, et al. - Men with clinically localized prostate cancer at one of nine UK centers were invited to take part in a treatment trial comparing active monitoring (AM), radical prostatectomy, and radiotherapy in order to assess outcomes according to treatment. Analyses according to treatment received revealed raised rates of disease-related events and cheaper rates of patient-reported harms in men managed by AM in comparison with men managed by radical treatment, and more substantial proof of more comprehensive prostate cancer mortality in the AM group.

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