Bendor CD, Bardugo A, Zucker I, et al. – Via performing a nationwide, population-based study involving 1,802,110 Israeli adolescents (mean age: 17.4 years ) who were examined before compulsory military service between 1979 and 2008 and whose data were linked to the Israeli National Diabetes Registry, researchers ascertained if a resolved single event of acute pancreatitis in childhood was correlated with incident diabetes in adulthood. They found that incident diabetes developed in 4.6% of individuals with resolved pancreatitis, defined as a history of a single event of acute pancreatitis with normal pancreatic function at enrollment, and 2.5% among the unexposed group. Resolved acute pancreatitis was linked to incident diabetes with an OR of 2.23 with adjustment for age, sex, and birth year. Childhood pancreatitis was related to a diagnosis of diabetes at a younger age, with 92% of diabetes case subjects given diagnoses before age 40 vs 47% in the unexposed group. Overall, in late adolescence, a history of acute pancreatitis in childhood with normal pancreatic function is a risk factor for incident type 2 diabetes, particularly in young adulthood.