Relationship between potentially inappropriate medications and the risk of hospital readmission and death in hospitalized older patients
Clinical Interventions in Aging Nov 08, 2019
Wang P, et al. – In this investigation involving hospitalized elderly patients aged ≥ 65 years who recruited from Beijing Fuxing Hospital, researchers compared the prevalence of potentially inappropriate medications (PIMs) by applying Beers and Chinese criteria, and they examined the link between PIMs and the risk of hospital readmission and mortality. A total of 508 participants were included, and they were observed for 12–36 months (or until patients’ death, if it came sooner). At least one PIM was identified in 69.3% of participants using the Beers criteria, and in 66.7% using the Chinese criteria. In the Beers and Chinese criteria, the most leading PIMs were proton-pump inhibitors and clopidogrel, respectively. Findings revealed that PIM use is highly prevalent in China. An increased risk of hospital readmission was observed in relation to PIMs defined using the Beers criteria. There was no link between PIM grouping defined using the Chinese criteria and hospital readmission. No connection was found between PIM grouping defined using either criteria and all-cause death. Based on these findings, the investigators recommended paying more attention to PIMs, performing routine PIM evaluations, and decreasing adverse health outcomes in elderly patients.
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