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Female reproductive history in relation to chronic obstructive pulmonary disease and lung function in UK biobank: A prospective population-based cohort study

BMJ Open Nov 07, 2019

Tang R, et al. - In a population-based prospective cohort study of UK Biobank enrolled across 22 centers in the UK between 2006 to 2010, experts examined whether aspects of female reproductive health could play a part in the risk of COPD among women. A range of female reproductive health indicators relative to the risk of COPD-related hospitalization/death (n = 271,271) using Cox proportional hazards regression, and lung function (n = 273,441) using linear regression was examined. Multiple female reproductive health indicators across the life course were found out to be related to COPD-related hospitalization/death and lung function. However, additional studies are needed to learn the opposing relationships of polycystic ovary syndrome/ovarian cysts, hormone replacement therapy and hysterectomy with COPD and objective measures of airway obstruction.
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