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Association of seminal angiotensinogen with sperm motility and morphology in male infertility

Andrologia Oct 28, 2019

Zhu X, Xie T, Zhan X, et al. - A total of 115 male individuals were enrolled, and semen parameters, seminal angiotensinogen (AGT) and the electrolytes including K+, Na+, Cl, P and Ca were assessed in order to evaluate whether abnormal levels of seminal AGT may be related to semen parameters in infertile males. According to the WHO 2010 criteria, the individuals were distributed into two groups ie, G1 group with normal semen parameters (n = 42) and G2 group with subnormal semen parameters (n = 73). In the G2 group vs G1 group, the level of seminal AGT was significantly greater. Furthermore, the level of AGT was negatively related to the percentage of total motility, progressive motility (PR) and morphologically normal forms. Therefore, this study implies that raised seminal AGT level is related to raised risk of asthenospermia and teratozoospermia.
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