Riviere P, Kumar A, Luterstein E, et al. - Researchers performed this retrospective cohort study to determine variations in prostate cancer-specific mortality (PCSM) between current smokers, past smokers, and never smokers diagnosed with prostate cancer (PC). The participants were treated for PC in the US Veterans Affairs healthcare system. A median follow-up of 5.9 years was performed in 73,668 men, including 22,608 (30.7%) current smokers, 23,695 (32.1%) past smokers, and 27,365 (37.1%) never smokers. For current, past, and never smokers, the 10-year incidence of PCSM was estimated to be 5.2%, 4.8%, and 4.5%, respectively. A higher risk of dying from PC as well as other causes of death was observed in correlation with smoking at the time of diagnosis. In contrast, there was no link between past smoking and PCSM, this indicates the possibility of smoking being a modifiable risk factor. PC diagnosis may signify a significant opportunity to discuss smoking cessation.