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Race/ethnicity and accuracy of self-reported female first-degree family history of breast and other cancers in the Northern California Breast Cancer Family Registry

Cancer Epidemiology, Biomarkers & Prevention Oct 18, 2019

John EM, Canchola AJ, Sangaramoorthy M, et al. - Researchers investigated whether cancer family history reports by women with breast cancer (probands) from the Northern California Breast Cancer Family Registry were accurate relative to 2 reference standards: personal cancer history reports by female first-degree relatives and California Cancer Registry records. They found that first-degree breast cancer family history was reported by non-Hispanic white, African American, and Asian American probands with high accuracy, although lower sensitivity for Hispanic white probands and those with low English language proficiency was observed. On comparing with the relatives' self-report of breast cancer as the reference standard, a sensitivity of 93% was yielded. On comparing with cancer registry records as the reference standard, high accuracy was reported, with a sensitivity of 95.5% for breast cancer.
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