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Acupuncture as adjunctive therapy for chronic stable angina: A randomized clinical trial

JAMA Oct 17, 2019

Zhao L, Li D, Zheng H, et al. - In this 20-week randomized clinical trial done in outpatient and inpatient settings at five clinical centers in China from October 10, 2012, to September 19, 2015, of 404 individuals who were randomized to get acupuncture on the acupoints on the disease-affected meridian (DAM), on the nonaffected meridian (NAM), receive sham acupuncture (SA), and receive no acupuncture (waitlist [WL] group), experts examined the efficiency and safety of acupuncture as adjunctive therapy to antianginal therapies in decreasing incidence of angina attacks in individuals with chronic stable angina. Across the four groups, baseline features were similar. In the incidence of angina attacks, the mean changes varied considerably among the four groups at 16 weeks, ie, in the DAM group vs the NAM group, in the DAM group vs the SA group, and in the DAM group vs the WL group, a higher decrease of angina attacks was noted. Thus, in comparison with acupuncture on the NAM, SA, or no acupuncture (WL), in mitigating angina, better advantages were exhibited by acupuncture on the DAM, as adjunctive treatment to antianginal therapy.
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