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Lifestyle behaviours and health measures of women at increased risk of breast cancer taking chemoprevention

European Journal of Cancer Prevention Oct 13, 2019

Pegington M, Evans DG, Howell A, et al. - Given chemoprevention is approved for women at increased breast cancer (BC) risk, researchers focused on adherence to healthy lifestyle recommendations among women receiving chemoprevention. They also compared lifestyle risk factors and health measures of these women with those of women in the general population, as well as examined the impact of chemoprevention on these. Participants were 136 premenopausal women receiving tamoxifen for the prevention of BC (Tam-Prev study) and age-matched women from the Health Survey for England 2012. A high prevalence of unhealthy lifestyle behaviours and health measures, including overweight and obesity (59.2%), low adherence to physical activity recommendations (30.6%), exceeding alcohol recommendations, suboptimal diets, presence of markers of cardiovascular disease risk and the metabolic syndrome, was observed in women receiving chemoprevention, similar to an age-matched English cohort. A significant attenuation in the rates of BC and other noncommunicable diseases could be achieved by improving these measures in women at heightened BC risk.
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