Sahin G, et al. - In this investigation involving 152 eyes recruited from Erzurum Region Training and Research Hospital, Turkey, researchers identified retinal nerve fiber layer thickness differences of ambylopic and fellow eyes and ambylopic and control eyes. The mean age of patients in the amblyopia group was 28.64 ± 8.23 years and in the control group was 32.23 ± 8.14 years. In ambylopic group, fellow eyes, and control eyes, the detected temporal retinal nerve fiber layer thickness (RNFL-T) was 77.27 ± 10.38 μ, 79.31 ± 9.53 μ, and 81.46 ± 9.86 μ, respectively, and superior RNFL-T was 136.23 ± 18.52 μ, 131.91 ± 13.80 μ, and 135.56 ± 14.94 μ respectively; nasal RNFL-T was 87.99 ± 13.05 μ, 82.16 ± 12.33 μ, and 85.50 ± 10.62 μ respectively. In the same order, 144.85 ± 18.39 μ, 140.55 ± 16.92 μ, and 143.47 ± 17.75 μ were the respective values for inferior RNFL-T in these groups. Findings revealed that there was no association between amblyopia and RNFL-T, so it was possible to ignore anisometropic amblyopia in patients with disease that could be detected and accompanied by RNFL thickness. For certain findings, further and larger scaled studies are required.