Alexander M, Loomis AK, van der Lei J, et al. - In this matched cohort study, data from population-based, electronic, primary healthcare databases from Italy (n = 1,542,672), Netherlands (n = 2,225,925), Spain (n = 5,488,397), and the United Kingdom (n = 12,695,046) were assessed to predict the risk of acute myocardial infarction (AMI) or stroke in people with non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis. Following adjustment for established cardiovascular risk factors, the diagnosis of NAFLD in current routine care did not seem to be correlated with AMI or stroke risk. Moreover, in adults with NAFLD, cardiovascular risk evaluation was found to be significant; however, it should be performed in a similar way as for the general population. Therefore, NAFLD was not significantly related to the outcomes investigated in this study.