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Performance of contrast-enhanced sonography vs MRI with a liver-specific contrast agent for diagnosis of hepatocellular adenoma and focal nodular hyperplasia

American Journal of Roentgenology Oct 11, 2019

Bröker MEE, Taimr P, de Vries M, et al. - Whether contrast-enhanced sonography (CEUS) with sulfur hexafluoride or MRI with the liver-specific contrast agent gadobenate dimeglumine affords a better tool to diagnose hepatocellular adenoma (HCA) and focal nodular hyperplasia (FNH), was investigated in this study performed on a cohort of consecutive patients. A prospective workup that involved CEUS and MRI with a liver-specific contrast agent was performed in patients who were referred to a tertiary center for hepatobiliary disease and had suspected HCA or FNH on MRI performed with an extracellular gadolinium-based contrast agent. In relation to concordant findings from CEUS and MRI with a liver-specific contrast agent, a definite diagnosis was made; cases with discordant findings were analyzed via histopathologic examination (HPE). For the diagnosis of HCA and FNH, a fair agreement was shown by the findings of CEUS and MRI with a liver-specific contrast agent. The diagnostic accuracy of MRI with a liver-specific contrast agent was significantly more common as compared with CEUS in cases with discordant findings that were HPE proven.
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