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Carbohydrate intake and risk of metabolic syndrome: A dose-response meta-analysis from observational studies

Nutrition, Metabolism & Cardiovascular Diseases Sep 17, 2019

Liu YS, Wu QJ, Xia Y, et al. – Because findings on the association of carbohydrate consumption and metabolic syndrome (MetS) risk has been shown to be inconsistent in previous epidemiological studies, researchers undertook this first dose-response meta-analysis to examine this impact. A total of 14 cross-sectional and 4 cohort studies (involving 284,638 participants and 69,554 MetS cases) were included in this analysis. Increased risk of MetS was reported in correlation with the highest vs the lowest carbohydrate consumption values, with moderate heterogeneity. Dose-response analysis revealed a linear link between carbohydrate intake and MetS risk, with a corresponding OR of 1.026 and significant heterogeneity at 5% energy from carbohydrate consumption. Overall, findings revealed a link between carbohydrate consumption and increased risk of developing MetS.

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