Twarog JP, et al. - By analyzing data from NHANES, researchers examined shifts in the national rates of blood donation among adults aged 20 years and older in the United States. A total of 49,512 US adults who were surveyed from 1999 to 2016 through the NHANES were included. Trends in recent blood donations were evaluated using Wald-chi square tests. Since 1999, the overall recent blood donation rate has hovered around 6%, with no significant shift during that time duration. A significant rise has been seen in the percentage of people aged 20 to 29 years with a recent blood donation during the last 2 decades. A significant fall in the percentage of people aged 30 to 39 years and people with a 4-year college degree or greater with a recent blood donation was also reported over the same time span. Although findings revealed no significant change in the national blood donation rate, a number of US subpopulations have shown significant shifts in donation rates.