Elderly males with or without existing osteoporotic vertebral fracture have much lower future vertebral fracture risk than elderly females: The MrOS (Hong Kong) year-4 follow-up spine radiograph study

Osteoporosis International Sep 08, 2019

Wáng YXJ, Che-Nordin N, Deng M, et al. - In this investigation, researchers recorded MrOS (Hong Kong)’s year-4 follow-up and contrasted the outcomes with the MsOS (Hong Kong) study. Of the elderly women with Genant grade-0, -1, -2, and -3 vertebral deformity (VD), 4.6%, 8%, 10.6%, and 28.9% had at least one VD progression or VD incident, respectively, at year-4 follow-up. According to Genant’s VD criteria and endplate or/and cortex fracture [ECF] (non-existent, ECF0; or existent, ECF1), spine radiographs of 1,500 Chinese males with baseline (mean age 71.7 years, range 65–91 years) and year-4 follow-up were assessed. Of individuals with Genant’s grade-0, 2.05% (25/1219) developed at least one VD progression or/and new VD, on the other hand, those with Genant’s grade-1, -2, and -3 VD, only 2% (3/149), 3.1% (3/96), and 2.8% (1/36) developed at least one VD progression/new VD, respectively. In elderly men, VD progression/new VD is much less common than in elderly women. The risk of developing ECF was greater for vertebrae with VD.
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