• Profile
Close

High prevalence of urogenital infection/inflammation in patients with azoospermia does not impede surgical sperm retrieval

Andrologia Sep 05, 2019

Pilatz A, Kilb J, Kaplan H, et al. - Via a prospective study of 71 patients with azoospermia subjected to an extensive andrological workup involving comprehensive microbiological diagnostics and testicular biopsy/testicular sperm extraction (TESE), researchers made a comprehensive assessment of the prevalence of urogenital tract infection/inflammation and its potential influence on sperm retrieval in azoospermic patients who underwent testicular biopsy/TESE. In 7% of patients, medical history suggested urogenital tract infection/inflammation, 11% harbored STIs, 14% exhibited notable bacteriospermia, 15% had seminal inflammation, 17% achieved the male accessory gland infection definition, and 27% had appropriate pathogens. At the testicular level, one patient had a swab positive for bacteria, no viruses were identified, tissue specimens never intimated pathogens, whereas, in 23% of samples, histopathology exhibited focal immune cell infiltrates. In obstructive and in nonobstructive azoospermia, the testicular sperm retrieval rate was 100% and 46%, respectively. None of the infection/inflammation-related variables was related to the success of sperm retrieval or inflammatory lesions in the testis. Among azoospermic men, the high prevalence of urogenital infection/inflammation underpins their role as important etiologic factors in male infertility. Nonetheless, this conclusion does not lead to the possibility of sperm retrieval at the time of surgery/TESE.
Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free.
  • 55 lakhs+ doctors trust M3 globally

  • Nonloggedininfinity icon
    Unlimited access to original articles by experts
  • Nonloggedinlock icon
    Secure: we never sell your data
  • Signing up takes less than 2 mins
Try M3 India / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay