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Risk factors and outcomes associated with treatment of asymptomatic bacteriuria in hospitalized patients

JAMA Sep 03, 2019

Petty LA, Vaughn VM, Flanders SA, et al. - Via a cohort study of 2,733 hospitalized adults with asymptomatic bacteriuria (ASB) at 46 hospitals participating in the Michigan Hospital Medicine Safety Consortium, researchers assessed factors related to the treatment of ASB among hospitalized patients and the relationship between treatment and clinical outcomes. Hospitalized patients with ASB usually get improper antibiotic therapy (82.7%). Altered mental status and abnormal urinalysis results were associated with receipt of antibiotics. Antibiotic treatment did not seem to be correlated with improved outcomes, instead it may be correlated with a longer length of hospitalization following urine testing. To possibly decrease inapt antibiotic use, stewardship efforts should focus on enhancing urine testing practices and management approaches for old patients with modified mental status.

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