Aronsson CA, Lee HS, af Segerstad EMH, et al. - In a multinational prospective birth cohort comprising of 6,605 genetically predisposed children, researchers examined whether the amount of gluten intake was related to celiac disease autoimmunity and celiac disease in genetically at-risk children. A total of 1,216 and 447 developed celiac disease autoimmunity and celiac disease, respectively. The incidence of both outcomes plateaued at the age of 2 to 3 years. For every 1-g/d increase in gluten intake, daily gluten intake was related to a greater risk of celiac disease autoimmunity and for every 1-g/d increase in gluten intake, daily gluten intake was correlated with greater risk of celiac disease. Hence, during the first 5 years of life, among genetically predisposed children, greater gluten consumption was linked to a heightened risk of celiac disease autoimmunity and celiac disease.