Jackson A, et al. - In young children with Down syndrome (DS), researchers assessed the connections between age, dysphagia, and medical comorbidities. They hypothesized that results from the swallow study are more probable to alter in younger infants and that dysphagia may be linked with medical comorbidities. In children with DS with initial swallow study at less than 12 months of age, they retrospectively collected results of videofluoroscopic swallow studies (VFSS) and fiberoptic endoscopic evaluation of swallowing (FEES) from 2010 to 2016. For this investigation, they involved 111 infants with 247 VFSS and 14 FEES. In 31.9% of infants less than 6 months and 51.3% of infants 6 to 12 months, deep laryngeal penetration and/or aspiration were found. Dysphagia was linked to laryngomalacia, pulmonary hypertension, pneumonia, and congenital cardiac disease. The authors verified that dysphagia is prevalent in infants with DS and comorbidities and given preliminary proof that results from the swallow study may alter more probably in children tested under the age of 6 months. Providers should consider that the findings of instrumental swallow studies may alter, especially if the test on a young infant has been completed.