Gao XP, Zheng CF, Liao MQ, et al. - Using data from the Multiparameter Intelligent Monitoring in Intensive Care Database III, researchers assessed the independent and combined impact of admission serum sodium and potassium on adverse clinical outcomes among patients with acute kidney injury (AKI). Ninety-day mortality in the intensive care unit (ICU) was assessed as the primary outcome. Participants included 13,621 ICU patients with AKI (mean age: 65.3 years; males: 55.4%). Findings revealed a U-shaped pattern of the association of admission serum sodium and potassium with survival in patients with AKI. A worse clinical outcome in patients with hyponatremia was predicted by hyperkalemia.