Beckmann K, Kinsella N, Olsson H, et al. - Via a register-based study that involved all men ≤ 75 years from Stockholm who were diagnosed with low-risk prostate cancer (PCa) from 2008 to 2014 (n = 4,336), experts examined whether there was any relationship between PCa screening frequency or former negative prostate biopsy and uptake of active surveillance (AS) among men with low-risk PCa. About 47% of men with low-risk PCa underwent AS. Uptake was related to elderly age, very low-risk disease, more recent diagnosis and absence of family history. Among men with low-risk PCa, none of the screening/biopsy measures (testing frequency, mean interval, prostate-specific antigen (PSA) velocity, greatest prediagnostic PSA or previous negative biopsy) were correlated with uptake of AS. Generalisability to settings with various policies and practices may be limited. Hence, among Swedish men with low-risk PCa, screening frequency and negative biopsy impact on the uptake of AS was not evident.