Metastasectomy for visceral and skeletal oligorecurrent prostate cancer
World Journal of Urology Aug 11, 2019
Battaglia A, Devos G, Decaestecker K, et al. - Researchers evaluated outcomes of surgical excision of visceral and skeletal prostate cancer (PCa) recurrence after primary treatment. Seventeen PCa individuals had metachronous visceral or skeletal oligometastatic recurrence after maximal local treatment. Fourteen, two, and one had visceral lesions, bone lesions, and an abdominal wall metastasis, respectively. During the time of metastasectomy, four were under active ADT. In 16 individuals, PSA was reduced following metastasectomy. PSA reduction of ≥ 50% was seen in 10 of the 13 ADT-naïve individuals. Sixteen developed a metastatic recurrence after metastasectomy; 11 were again oligometastatic, amenable for repeated metastasis direct therapy. The median time to metastatic recurrence was 14 months. In 21 procedures, 8% Clavien–Dindo grade 3–4 complications was noted. In conclusion, long-term disease-free periods at a low rate of serious complications could be the result from removing metastasis to the bone and viscera.
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