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Prevalence of hospitalization caused by adverse drug reactions at an internal medicine ward of a single centre in Japan: A cross-sectional study

BMJ Open Aug 09, 2019

Komagamine J, et al. - Via performing a single-center cross-sectional study involving the electronic medical records of 1,545 consecutive hospital admissions to an internal medicine ward due to acute medical illnesses from April 2017 to May 2018, researchers assessed the prevalence of adverse drug reactions (ADRs) resulting in hospitalization, and evaluated the preventability of these ADRs in Japan. Of 1,545 hospitalizations, 153 were due to 200 ADRs. Nearly two-thirds of all ADRs leading to hospitalization were caused by cardiovascular agents (n = 46), antithrombic agents (n = 33), psychotropic agents (n = 29), and NSAIDs (n = 24). Of the 153 hospitalizations caused by ADRs, 102 were preventable. Thus, 1 in every 10 hospitalizations were caused by ADRs—a statistic comparable to other countries. Most of these hospitalizations were preventable.

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