Hu C, Duijts L, Erler NS, et al. - In this investigation, researchers identified eczema phenotypes during childhood and their associations with early-life environmental and genetic factors. Phenotypes based on parent-reported physician-diagnosed eczema from age 6 months to 10 years were identified using latent class growth analysis in this study ubvikvubg 5,297 children from a multiethnic population-based prospective cohort study. Using postal questionnaires, information on environmental factors was obtained. The following five eczema phenotypes were identified: never (76%), early transient (8%), mid-transient (6%), late transient (8%), and persistent eczema (2%). Investigators found that early transient and persistent eczema were most common in firstborn children, those with eczema, allergy or asthma in their parents, and those with persistent wheezing. Eczema phenotypes were connected differently with male sex and Asian and African ethnicity and could, therefore, be helpful for forecast purposes. Maternal education, breastfeeding, daycare attendance, and pet exposure were not linked to eczema phenotypes.