Park YS, et al. - The clinical course of acute kidney injury (AKI) following out-of-hospital cardiac arrest (OHCA) was investigated as was if recovery from AKI impacted the outcomes of OHCA. For this retrospective multicenter cohort study, researchers screened 3,697 adult OHCA patients treated with targeted temperature management from six hospitals; 275 of these were ultimately included. Development of AKI was reported in 64% patients and recovery from AKI was noted 39% patients. Most patients developed AKI within three days of return of spontaneous circulation (89%, median time to AKI development 1 [1–2] day) and recovery was reported in patients within seven days of return of spontaneous circulation (86%, median time to AKI recovery 3 [2–7] days). The AKI non-recovery group had a significantly longer duration of AKI than the AKI recovery group. Recovery from AKI was noted to be an strong predictor of survival and good neurological outcome at discharge.