Suvila K, et al. - Among middle-aged participants (n=26,80; mean age: 50 ± 4 years; 57% women) from the Coronary Artery Risk Development in Young Adults study, researchers assessed the link between hypertension onset age and hypertensive target end-organ damage (TOD). They reported odds ratios of 2.29 for left ventricular hypertrophy, 2.94 for coronary calcification, 1.12 for albuminuria, and 2.06 for diastolic dysfunction, in relation to hypertension onset at age < 35 years vs normotensive individuals. In contrast, no link was evident between hypertension onset at age ≥ 45 years and increased odds of TOD. In order to avoid hypertensive complications in high-risk individuals, evaluating the age of hypertension onset is important, suggested the authors.