Bongers PJ, et al. - In long-term follow-up of individuals with benign thyroid biopsy results, researchers used data from an entire population to determine the risk of being diagnosed with thyroid cancer. The results seemed to suggest the occurrence of thyroid nodules in more than 50% of the general population. Historically, clinicians indefinitely followed up on thyroid nodules characterized as benign, often with multiple subsequent growth-based biopsies. Current evidence from sampled populations indicates that after long-term follow-up, the incidence of malignant neoplasms among benign thyroid nodules is small.